Surgery Bioinformatics Analyst

Required Qualifications

• Doctorate in the life sciences, computer science or engineering. Candidates must have significant bioinformatics experience.
• 3+ years of research experience in genomics, genetics, molecular biology or computational biology.
• Hands-on experience in developing and carrying out data analytical strategies and pipelines for analyzing datasets from high-throughput platforms such as next generation sequencing.
• Experience/general proficiency with UNIX shell environment, a programming language (ideally R or python), plus currently used tools (e.g. BWA, HISAT2, GATK, freebayes, Cell Ranger, Seurat, etc.).
• Must be able to understand and translate life scientist researchers' scientific goals into analytical strategies and process requirements.
• Must be able to function as part of an interactive team while demonstrating self-initiative to achieve the project's goals and the group's mission.
• Critical and independent thinking.
• Excellent oral and written English communication and interpersonal skills.

Preferred Qualifications

• Experience with single-cell RNA-seq and spatial transcriptomics data analysis is strongly preferred.
• Research background in human or mammalian genetics.
• Advanced statistical and data modeling skills.

The Research Informatics Solutions (RIS) group within the University of Minnesota Supercomputing Institute (MSI) is hiring a full-time Bioinformatics Analyst to support biomedical research for the Department of Surgery at the University of Minnesota. The analyst in this position will conduct cutting-edge bioinformatics analyses in close collaboration with a diverse set of biomedical labs within the Surgery department. The successful candidate will join the twelve-person RIS group at MSI.

The candidate will work with researchers and clinicians in Surgery on a broad variety of basic and translational biomedical research projects that will impact human health, including projects in transplant biology, immune response in disease, and the transcriptomic response to surgery. Many of these projects involve single-cell sequencing and spatial transcriptomics, so there is ample opportunity for the analyst to break new ground by exploring novel methods and tools.

As part of an interdisciplinary team, successful candidates will have the responsibility to:

• Serve as a bioinformatics analyst and developer for research projects for the Department of Surgery.
• Serve as a liaison between the Surgery Department and MSI.
• Consult with Surgery researchers on experimental design and planning.
• Design and implement appropriate informatics workflows.
• Identify and integrate new, cutting-edge molecular technologies and analysis methods as they become useful for research purposes (e.g., single-cell expression profiling, long-read sequencing, spatial transcriptomics, etc.).
• Appropriately document and present methods and results in both internal and external reports, publications, and presentations.

The ideal candidates will have advanced knowledge of next generation sequencing technologies with demonstrated practical experience in developing and carrying out analytical strategies in the context of NGS applications (e.g. RNA-seq including single cell and spatial transcriptomic datasets, DNA variant detection, metagenomics, etc.).

The Research Informatics Solutions (RIS) group at the Minnesota Supercomputing Institute (MSI) was formed in 2011, leveraging MSI’s rich computational environment to foster innovative bioinformatics collaboration with researchers across the University and Minnesota.

The Minnesota Supercomputing Institute (MSI) is a core research facility of the University of Minnesota (U of M), part of Research Computing within the Office of the Vice President for Research. MSI provides advanced research computing infrastructure and expertise to the University's research and scholarly community and the State of Minnesota in order to advance and accelerate research and foster innovation and discoveries through advanced computing technologies, scientific computing and informatics, application development, and services. The Institute currently supports over 900 different groups with over 4500 active users spanning the sciences, engineering, life sciences, medicine, and social sciences.

The Office of the Vice President for Research (OVPR) and the Minnesota Supercomputing Institute (MSI) endorse a “work with flexibility” approach that offers a welcoming and flexible work environment where everyone is inspired to do their best. Work location options at the University of Minnesota include working fully remote, partially remote, or entirely in the office and are based on the work of the position. Some on-site work may be necessary for certain positions, even those designated as fully remote.

This MSI position has responsibilities that will require on-site work at least 50% of the time, with options for management-approved flexible work arrangements. Offices for these staff positions are located in Walter Library on the Twin Cities, East Bank Campus.

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-UOHR (8647).

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu.

MSI and Surgery have a strong commitment to the University’s goal of creating a positive and inclusive campus climate by advancing equity and diversity. We aim to hire high-potential people with varying identities and backgrounds. The analyst in this position must have excellent communication skills, strong analytical, computational, and life sciences training or experience, and be comfortable working independently and as part of an interdisciplinary research team on diverse projects.

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

Please note: All employees at the University of Minnesota are required to comply with the University’s Administrative Policy: COVID-19 Vaccination and Safety Protocol by either providing proof of being fully vaccinated on their first day of employment, or complete a request for an exemption for medical exemption or religious reasons. To learn more please visit: https://safe-campus.umn.edu/return-campus/get-the-vax

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.