Scientist II, Biological Sciences (non-PhD)

Deciphera is a biopharmaceutical company focused on discovering, developing and commercializing important new medicines to improve the lives of people with cancer. We are leveraging our proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines.

In addition to advancing multiple product candidates from our platform in clinical studies, QINLOCK® is Deciphera’s FDA-approved switch-control kinase inhibitor for the treatment of fourth-line gastrointestinal stromal tumor (GIST). QINLOCK is also approved for fourth-line GIST in Australia, Canada, China, and Hong Kong.

Deciphera (NASDAQ: DCPH) is a publicly traded company headquartered in Waltham, Massachusetts. Our state-of-the-art research facility is located in Lawrence, Kansas.

We offer an outstanding culture and opportunity for personal and professional growth based on our “PATHS” Core Values:

• Patients – places the importance of improving the lives of patients and their caregivers at the forefront of every day’s work.
• Accountability – for our performance and the way we work with coworkers and other stakeholders.
• Transparency – in our intent and actions to both internal and external stakeholders.
• Honesty and Integrity – fosters trust and strives to deliver on our and the company’s promises.
• Stewardship – values and uses wisely the resources and investments provided to the company.

Position Summary:

We are seeking a Scientist II, Biological Sciences to join our drug discovery group. This position will work with the Biological Sciences team to discover new kinase inhibitors for the treatment of cancer.

This position will report to a Principal Investigator, Biological Sciences and is located in our state-of-the-art research facility near the University of Kansas in Lawrence, Kansas.

Key Responsibilities:

• Independently develop and perform primary screening of small molecules utilizing cell-based assays. Primary responsibility will be in the area of screening small molecule kinase inhibitors
• Perform routine mammalian cell culture
• Together with supervisor, responsible for validating new biochemical or cell biology-based assays and troubleshooting when needed to establish reliable screening platforms
• Work with the drug discovery team to design and implement assays and experiments which test hypotheses and evaluate mechanisms of kinase inhibitors
• Track and record data into corporate database
• Generate reports and presentations as required by the organization
• Effectively work in a team environment: communicate and plan research with other chemists, biologists, and pharmacologists also working on the project
• Adhere to corporate policies including safety, FDA compliance and regulatory matters
• Values other people and promotes the welfare of the organization and colleagues
• Perform other duties as requested

• Degree MS or BS in biochemistry or related field
• Years of experience MS 2-4; BS >4
• Technical skills required: laboratory experience with cell biology techniques including western blot, cell viability assays, ELISA’s, mammalian cell culture, CRISPR cell line generation, qRT-PCR, flow cytometry and lentiviral transductions
• Experience in Immunology or Virology is strongly preferred
• Previous experience in a biotech or pharmaceutical company preferred
• Other: Computer skills with MS Office (Excel, Word, PPT) and scientific graphing software (Prism)

All your information will be kept confidential according to EEO guidelines.

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements and to learn more about how we can increase diversity in our candidate pool, we invite you to voluntarily provide demographic information in a confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. Our commitment to increasing diversity in our candidate pool does not affect our commitment to equal employment opportunity, including our ongoing commitment to make all hiring and other employment decisions solely on a nondiscriminatory basis.