Research Associate

Employment Type: Staff - Regular Employee Class: Salaried Full Time HSC Bargaining Unit: BU Exempt Shift: 1 Work Hours: 0830 - 1700 Hours Per Week: 40 FTE: 1 Location: Client Admin Location Department: Dept. of Cancer Biology Number of Openings: 1 Salary Range: $ 38,100.00 - 47,667.00 Grade: Salaried HSC - J104 Float: N/A Rotate: N/A On Call: N/A Travel: N/A Weekend/Holiday: Yes Requisition ID: req3694 Position Control Number (PCN): T88209 Posting Period: 8/4/2021 - 8/13/2021

Serves as a research associate will perform various general and advanced laboratory tasks, maintain the mice colony and conduct animal experiments to study the role of proteotoxic stress response in pancreatic tumoral lipid metabolism and tumorigenesis. Assist in grant and publication preparation, lab management, training Ph.D. students and new staff.

Education/experience/licensing:

Education and training are generally associated with a B.S. with 3-year laboratory experiences or M.S. or Ph.D. Degree in cancer biology, physiology, pharmacology, or related field.

Prior laboratory research experience is preferred:

Molecular biological techniques: Gene cloning, Western blot, PCR and real-time PCR, RNAi, overexpression analysis, proximity ligation assay (PLA), Flow Cytometry analysis, Chromatin immunoprecipitation (CHIP), in vitro kinase assay, and some knowledge on bioinformatics.

Cell culture and transfection: knowledge and experience in cell cultures such as primary tumor cell, mammalian cell, and embryonic stem cell. Cell lipid metabolism techniques, cell transfection, proliferation, apoptosis, and autophagy experiments.

Molecular imaging techniques: Confocal imaging, immunocytochemical staining, immunohistochemistry staining, transmission electron microscopy.

Animal study: Experience with genetically engineered mouse models will be prioritized, mice handling, colony maintenance, and genotyping, blood and tissue collection, xenograft and orthotopic implantation, mice Eco-MRI body composition analysis, i.p./i.v. injection, oral gavage, and drug efficacy studies.

Communication and other skills:

Ability to lead a project with minimal supervision in an organized fashion.

Capacity to work collaboratively with investigators in a multidisciplinary academic setting.

Laboratory management experiences are preferred, but not required.

Excellent oral and written communication skills

Experience using advanced Excel functions such as tables, graphs, statistical formulas, Basic editor, and other software such as GraphPad Prism analysis and Image J are preferred.

Experience in rodent husbandry or veterinary care is useful, but not required. Knowledge of the methods, materials, and equipment used in animal care and laboratory activities.

Work in the standard research lab with biosafety level 2.

The above list of duties is intended to describe the general nature and level of work performed by people assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the people so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct and control the work of employees under his/her supervision.

The University of Toledo is an equal opportunity, affirmative action employer. The University of Toledo does not discriminate in employment, educational programs, or activities on the basis of race, color, religion, sex, age, ancestry, national origin, sexual orientation, gender identity and expression, military or veteran status, disability, familial status, or political affiliation.

The University of Toledo provides reasonable accommodation to individuals with disabilities. If you require accommodation to complete this application, or for testing or interviewing, please contact the Human Resources Department at 419-530-4747 between the hours of 8:30AM and 5:00PM or apply online for an accommodation request.

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