Postdoctoral Fellow - Cancer Immunotherapy: CAR T Cell Development

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
The Department of Hematology, Toni Stephenson Lymphoma Center under the direction of Dr. Larry Kwak at the Beckman Research Institute of the City of Hope is looking for a talented Postdoctoral Fellow.

Highly motivated and self-directed applicants interested in translational research in cancer immunotherapy are strongly encouraged to apply. However, applicants with related training and experience will be given priority.

For more scientific background, please refer to our publications:

Science 2002 Nov 1; 298(5595):1025-9
Nature Medicine 2014 Jun; 20(6):676-81
Nature Medicine 2005 Sep; 11(9):986-91
Clin Cancer Res 2017 Mar; 24(5):1114-1123

Highly motivated and self-directed applicants interested in translational research in cancer immunotherapy are strongly encouraged to apply. However, applicants with related training and experience will be given priority.

The ideal candidate must have extensive experience in cancer immunology, CAR T-cell development, tumor-microenvironment interactions, flow cytometry, and cell culture.

Key Responsibilities include:

The Postdoctoral Fellow’s function is to support the research and activities of the research laboratory under the direction and mentorship of the Principal Investigator.
This position will interact and collaborate with a team of scientists highly trained in translational research of cancer immunotherapy.
Fellows will bring their skills, knowledge, and experience to be actively involved in the development of immunotherapies for blood cancer.

Qualifications
Basic education, experience and skills required for consideration:

A Ph.D. degree in life or biomedical sciences, or a related discipline is required, with research experience;
A track record of publications in peer-reviewed scientific journals;
Solid knowledge in cancer immunology, molecular and cell biology, and biochemistry;
Excellent communication skills with the ability to work independently and as part of a team;
Under the direction of the Principal Investigator, effectively lead a project in a translational research environment in order to successfully meet project goals;
Ability to perform and prioritize multiple simultaneous tasks;
Ability to design and execute experiments, critically interpret experimental results, and present data in a cogent and meaningful manner;
Ability to participate in the preparation of grant applications and publications.

Preferred education experience and skills:

Experienced in T cell based therapy and CAR-T cell development is preferred;
Experience in handling mice, multi-parameter flow cytometry, fast protein liquid chromatography systems is preferred.

Additional Information:

For more information on Dr. Kwak’s research, please click here .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.