Associate Scientist

Company Summary: Korro Bio is a privately held biotechnology company focused on the discovery and development of a new class of precision genetic medicines utilizing our propriety RNA editing platform, OPERA. Our portfolio of innovative RNA therapies has the potential to propel genetic medicine beyond rare genetic diseases into larger patient populations with common diseases. Korro enjoys support from a committed group of institutional investors, and recently completed a $116 million Series B financing round to advance our current and future work. We are located in Cambridge, Massachusetts.

We are collaborative and united by a common mission. We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases. Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization. They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work.

Position Summary: We are seeking a highly motivated, Associate Scientist to join our High-Throughput Screening group. He/She will be responsible for the design, execution and analysis of a variety of high throughput screens and will participate in the development and scaling of novel assays as we continue to build our RNA editing platform. The candidate must have demonstrated proficiency in the deployment of cell-based models and assays for drug candidate screening. In addition, the candidate will help design, validate, and implement high throughput NGS and qPCR-based assays. The candidate should have a proven ability to design and implement thoughtful and well controlled experiments. The right candidate should also be comfortable working with various types of automated high throughput equipment. The candidate will be a motivated team player, have excellent interpersonal and communication skills and be able to balance multiple high-priority tasks in a rapidly changing environment.

Key Responsibilities:

• Help design, validate, and implement high throughput NGS and qPCR-based assays using various types of automated high throughput equipment.
• Deploy cell-based models and assays to screen drug candidates.
• Participate in the development and scaling of various in vitro assays.
• Collect, interpret data and present research updates to different project groups.

Required Qualifications:

• MS with 0-2 years of experience or BS with 3-5 years of experience in molecular and/or cell biology, or related field.
• Experience with cell cultures and cell-based assays in 96 and, preferably, in 384-well format.
• Broad experience in the application of biochemical and cell-based techniques such as mammalian cell cultures, transfections, various immunoassays such as Western Blotting, SDS-PAGE and probe-based qPCR.
• Familiarity in the use of lab automation, liquid handling and HTS instrumentation is preferred.
• The ability to learn and implement new techniques and adapt rapidly are essential. Excellent attention to detail, time management, and documentation.
• The candidate must be able to analyze, report and communicate data rigorously.
• Ability to multitask and successfully interact with a diverse team of scientists to deliver quality data and results.
• Clearly present research updates to different project teams.

Other Knowledge, Experience or Skills recommended:

• Hands-on assay execution and troubleshooting skills and proficiency with different throughput screening formats, screening technologies, and laboratory automation.
• Experience in employing various sequencing technologies such Sanger, amplicon NGS and/or whole genome RNA transcriptome sequencing.
• An understanding of molecular cloning, plasmid and primer design and related techniques.

Benefits: Korro offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance, a dependent care flexible spending account and a Company-funded health savings account and free parking.