Next Generation Sequencing (NGS) and Molecular Bioinformatics Analyst Details

Next Generation Sequencing (NGS) and Molecular Bioinformatics Analyst

University of Pennsylvania - Philadelphia, PA

Employment Type : Full-Time

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title
Next Generation Sequencing (NGS) and Molecular Bioinformatics Analyst

Job Profile Title
Research Specialist D

Job Description Summary
As June/Gill laboratory Next Generation Sequencing (NGS) and Molecular Bioinformatics Analyst, this position will report to Drs. Young and Gill. This individual will support NGS platform establishment and development, generation of NGS libraries, and quality control analyses, and writing associated Standard Operating Procedures (SOP) for library preparation, and NGS data acquisition. This hire will coordinate with the NGS sequencing Core to ensure timely analyses of single cell RNA-seq libraries and retrieval of resulting data. One of the key responsibilities of this position will be implementation of NGS data analysis pipelines in the June/ Gill laboratories selecting, adapting and utilizing appropriate software while working with vendors, bioinformatics cores and other resources. The hire will interface with laboratory members to provide bioinformatics support in the analysis of sequencing data, and figure and slide generation. This position may also assist with the analysis of molecular data from other advanced instrumentation in June/Gill laboratories, such as Nanostring's GeoMx DSP, nCounter and A5 Symphony. The duties of this position may require occasional working during weekends or University Holidays

Job Description

As June/Gill laboratory Next Generation Sequencing (NGS) and Molecular Bioinformatics Analyst, this position will report to Drs. Young and Gill. This individual will support NGS platform establishment and development, generation of NGS libraries, and quality control analyses, and writing associated Standard Operating Procedures (SOP) for library preparation, and NGS data acquisition. This hire will coordinate with the NGS sequencing Core to ensure timely analyses of single cell RNA-seq libraries and retrieval of resulting data. One of the key responsibilities of this position will be implementation of NGS data analysis pipelines in the June/ Gill laboratories selecting, adapting and utilizing appropriate software while working with vendors, bioinformatics cores and other resources. The hire will interface with laboratory members to provide bioinformatics support in the analysis of sequencing data, and figure and slide generation. This position may also assist with the analysis of molecular data from other advanced instrumentation in June/Gill laboratories, such as Nanostring's GeoMx DSP, nCounter and A5 Symphony. The duties of this position may require occasional working during weekends or University Holidays

Qualifications
Master's Degree with 3-5 years of related experience or equivalent combination of education and experience is required. . The successful candidate must have prior experience in the following methodologies: DNA/RNA isolation, sequencing library preparation, knowledge of NGS technologies and data analysis. Prior experience with process and assay automation is required. Prior experience with human clinical trials and working in fast paced environment is preferred. Strong communication skills required. Prior experience working with equipment vendors and cores is required

This position is contingent upon funding.

Working Conditions
Office, Library, Computer Room; Requires extensive safety

Physical Effort
Typically sitting at a desk or table; Occasional lifting 25 lb. or less

Job Location - City, State
Philadelphia, Pennsylvania

Department / School
Perelman School of Medicine

Pay Range
$50,684.00 - $91,232.00

Affirmative Action Statement
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.