Employment Type : Full-Time
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. POSITION Associate Director, Translational Medicine SUPERVISOR Director, Translational Medicine DEPARTMENT Heme Translational Development Disease Team, Translational Medicine LOCATION Summit West Campus PREREQUISITES PhD in life sciences or medical sciences, and a minimum of 10 years of directly relevant biotechnology and/or pharmaceutical industry experience. Bristol-Myers Squibb is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture. BMS R&D is at a critical and exciting phase of development. As it expands and integrates its portfolio including small molecules, biologics and cell therapies, there is an opportunity for a dynamic and resourceful individual to lead a team of innovative laboratory scientists that are addressing scientific questions in support of programs managed by the Translational Medicine group at our site in Summit, NJ. Translational Medicine at BMS Translational Medicine is part of the Global Research and Early Development organization in BMS and leads late stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. Translational Medicine Hematology drives strategy for multiple disease areas of interest including Myeloma, Lymphoma, CLL, AML, MDS, anemias and other hematological malignancies. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics. Summary Reporting to Director, Translational Medicine, the incumbent will be part of the translational group based in Summit NJ and will manage the scientific and preclinical laboratory component of multiple late stage hematology programs (phase 2 and beyond). Key responsibilities of this role are to serve as a key scientific lead for the preclinical support of asset programs through mechanism of action-based studies, differentiation from standard of care molecules, combination rationale and resistance mechanisms. He/She will work with translational scientists, disease leaders within translational medicine and thematic research centers in early development within the company. In addition, guidance of laboratory scientists to generate data in support of clinical development decisions will be required. Responsibilities Leads a group of scientists who execute the preclinical/laboratory support component of late stage BMS portfolio of compounds to support annual goals and objectives for the Heme translational medicine group (for internal /external, collaborations, compound specific plans etc). Responsible for delivering data in support of translational strategies including biomarkers, patient selection hypotheses, dose and schedule, combination strategies, resistance mechanisms and differentiation Report directly to the head of the laboratory and manage laboratory scientists to integrate clinical questions into lab-based translational research internally and externally Interfaces with early development scientist to ensure seamless flow of information for assets which are entering the remit of translational medicine Manages and supervises a portfolio of preclinical collaborations across the pipeline compounds for clinical assets Assists in managing key strategic and/or collaborative projects along with TM scientists Communicates regularly and prepares and makes presentations within the department, externally and to senior management as required Assists in developing and maintaining group budget and workforce plan PhD or MD/PhD with at least 10 years of relevant work experience. Experience including drug development in an industry setting, especially hematology indications is a plus. Strong publication record and track record in large and/or small companies, leading innovative efforts within the laboratory setting to achieve defined goals and support clinical development Excellent communication, managerial and scientific qualities are expected Ability to interact effectively across boundaries using influencing and relationship building skills. Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals. Technical Skills In-depth understanding of cancer biology (hematology a plus), clinical landscape, evolving technologies, competitive scenario Good understanding of drug development process in an industry setting with clear examples of success Understanding of late-stage drug and translational development process Ability to work with disease teams/experts to develop preclinical strategies to support clinical development and life cycle management Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, and strategic communications Proven scientific/project leadership expertise (working in teams, managing collaborations, people/projects) Basic understanding of IP, contracting terms and provisions Other Attributes A problem solver who creatively and knowledgeably transcends departmental function to act as a resource to entire research effort and senior managers in development. Identifies issues early and proposes innovative solutions. Communicates within the larger organization and external community. Provides expert guidance to multi-disciplinary teams and senior management. A leader whose scope of influence stretches across the company A leader who influences external scientific community. Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
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